106266

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2513357..2513541 Replicon chromosome
Accession NZ_CP029673
Organism Staphylococcus aureus strain AR_0220

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CSB76_RS13265 Protein ID WP_000482652.1
Coordinates 2513434..2513541 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2513357..2513417 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB76_RS13240 2508812..2508979 - 168 Protein_2408 hypothetical protein -
CSB76_RS13250 2509210..2510943 - 1734 WP_110417930.1 ABC transporter ATP-binding protein/permease -
CSB76_RS13255 2510968..2512731 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 2513357..2513417 + 61 - - Antitoxin
CSB76_RS13265 2513434..2513541 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
CSB76_RS13270 2513675..2514061 - 387 WP_000779360.1 flippase GtxA -
CSB76_RS13275 2514329..2515471 + 1143 WP_001176863.1 glycerate kinase -
CSB76_RS13280 2515531..2516190 + 660 WP_000831298.1 membrane protein -
CSB76_RS13285 2516372..2517583 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CSB76_RS13290 2517706..2518179 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T106266 WP_000482652.1 NZ_CP029673:c2513541-2513434 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106266 NZ_CP029673:c2513541-2513434 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106266 NZ_CP029673:2513357-2513417 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References