Detailed information of TA system TA106224

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 315100..315282
• Replicon: chromosome
• Accession: NZ_CP029669
• Organism: Staphylococcus aureus strain AR_0223

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CSB79_RS02005
• Protein ID: WP_001801861.1
• Coordinates: 315187..315282 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	315100..315159 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSB79_RS01990	314238..314615	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
CSB79_RS01995	314809..314985	+	177	Protein_329	transposase	-
CSB79_RS02000	314963..315064	-	102	WP_001791893.1	hypothetical protein	-
-	315100..315159	+	60	-	-	Antitoxin
CSB79_RS02005	315187..315282	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
CSB79_RS02015	315485..315628	+	144	WP_001549059.1	transposase	-
CSB79_RS02025	316232..316615	+	384	WP_000070811.1	hypothetical protein	-
CSB79_RS02030	316626..316802	+	177	WP_000375476.1	hypothetical protein	-
CSB79_RS02035	316804..316989	+	186	WP_000809857.1	hypothetical protein	-
CSB79_RS02040	317103..317744	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
CSB79_RS02045	317962..318513	-	552	WP_000414205.1	hypothetical protein	-
CSB79_RS02050	318611..318955	-	345	WP_000627551.1	DUF3969 family protein	-
CSB79_RS02055	318996..319622	-	627	Protein_339	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	282009..352722	70713

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T106224 WP_001801861.1 NZ_CP029669:c315282-315187 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T106224 NZ_CP029669:c315282-315187 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT106224 NZ_CP029669:315100-315159 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin