Detailed information of TA system TA106215

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 925311..925493
• Replicon: chromosome
• Accession: NZ_CP029667
• Organism: Staphylococcus aureus strain AR_0225

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CSB81_RS05475
• Protein ID: WP_001801861.1
• Coordinates: 925398..925493 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	925311..925370 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSB81_RS05460	924449..924826	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
CSB81_RS05465	925020..925196	+	177	Protein_956	transposase	-
CSB81_RS05470	925174..925275	-	102	WP_001791893.1	hypothetical protein	-
-	925311..925370	+	60	-	-	Antitoxin
CSB81_RS05475	925398..925493	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
CSB81_RS05485	925696..925839	+	144	WP_001549059.1	transposase	-
CSB81_RS05495	926443..926826	+	384	WP_000070811.1	hypothetical protein	-
CSB81_RS05500	926837..927013	+	177	WP_000375476.1	hypothetical protein	-
CSB81_RS05505	927015..927200	+	186	WP_000809857.1	hypothetical protein	-
CSB81_RS05510	927314..927955	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
CSB81_RS05515	928173..928724	-	552	WP_000414205.1	hypothetical protein	-
CSB81_RS05520	928822..929166	-	345	WP_000627551.1	DUF3969 family protein	-
CSB81_RS05525	929207..929833	-	627	Protein_966	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	792389..962450	170061

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T106215 WP_001801861.1 NZ_CP029667:c925493-925398 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T106215 NZ_CP029667:c925493-925398 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT106215 NZ_CP029667:925311-925370 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin