106205

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 546963..547226 Replicon chromosome
Accession NZ_CP029667
Organism Staphylococcus aureus strain AR_0225

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSB81_RS03040 Protein ID WP_001802298.1
Coordinates 546963..547067 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 547062..547226 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB81_RS03015 542347..543129 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
CSB81_RS03020 543197..544054 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CSB81_RS03025 544759..544851 - 93 WP_001790138.1 hypothetical protein -
CSB81_RS03030 545140..546276 + 1137 WP_000115564.1 SAP domain-containing protein -
CSB81_RS15505 546319..546802 + 484 Protein_535 recombinase family protein -
CSB81_RS03040 546963..547067 + 105 WP_001802298.1 hypothetical protein Toxin
- 547062..547226 - 165 - - Antitoxin
CSB81_RS03045 547567..548658 - 1092 WP_000495671.1 lytic regulatory protein -
CSB81_RS03050 548924..549904 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CSB81_RS03055 549906..550226 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSB81_RS03060 550378..551043 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106205 WP_001802298.1 NZ_CP029667:546963-547067 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106205 NZ_CP029667:546963-547067 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT106205 NZ_CP029667:c547226-547062 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References