Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 432487..432750 Replicon chromosome
Accession NZ_CP029664
Organism Staphylococcus aureus strain AR_0226

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSB82_RS02325 Protein ID WP_001802298.1
Coordinates 432487..432591 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 432586..432750 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB82_RS02300 427871..428653 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
CSB82_RS02305 428721..429578 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
CSB82_RS02310 430283..430375 - 93 WP_001790138.1 hypothetical protein -
CSB82_RS02315 430664..431800 + 1137 WP_000115564.1 SAP domain-containing protein -
CSB82_RS15295 431843..432326 + 484 Protein_429 recombinase family protein -
CSB82_RS02325 432487..432591 + 105 WP_001802298.1 hypothetical protein Toxin
- 432586..432750 - 165 - - Antitoxin
CSB82_RS02330 433091..434182 - 1092 WP_000495671.1 lytic regulatory protein -
CSB82_RS02335 434448..435428 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
CSB82_RS02340 435430..435750 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSB82_RS02345 435902..436567 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106188 WP_001802298.1 NZ_CP029664:432487-432591 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106188 NZ_CP029664:432487-432591 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT106188 NZ_CP029664:c432750-432586 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References