Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 140918..141102 Replicon chromosome
Accession NZ_CP029664
Organism Staphylococcus aureus strain AR_0226

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag CSB82_RS00730 Protein ID WP_000482650.1
Coordinates 140918..141025 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 141042..141102 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB82_RS00705 136280..136753 + 474 WP_000456489.1 GyrI-like domain-containing protein -
CSB82_RS00710 136876..138087 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
CSB82_RS00715 138269..138928 - 660 WP_000831298.1 membrane protein -
CSB82_RS00720 138988..140130 - 1143 WP_001176863.1 glycerate kinase -
CSB82_RS00725 140398..140784 + 387 WP_000779358.1 flippase GtxA -
CSB82_RS00730 140918..141025 + 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
- 141042..141102 - 61 - - Antitoxin
CSB82_RS00740 141653..143416 + 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
CSB82_RS00745 143441..145174 + 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
CSB82_RS00755 145405..145572 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T106185 WP_000482650.1 NZ_CP029664:140918-141025 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106185 NZ_CP029664:140918-141025 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106185 NZ_CP029664:c141102-141042 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References