Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 782631..782893 Replicon chromosome
Accession NZ_CP029658
Organism Staphylococcus aureus strain AR_0467

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSC52_RS04115 Protein ID WP_001802298.1
Coordinates 782631..782735 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 782730..782893 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC52_RS04090 779428..780210 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
CSC52_RS04095 780278..781135 + 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
CSC52_RS04105 781793..781951 - 159 WP_001792784.1 hypothetical protein -
CSC52_RS04115 782631..782735 + 105 WP_001802298.1 hypothetical protein Toxin
- 782730..782893 - 164 - - Antitoxin
CSC52_RS04120 783168..784259 - 1092 WP_000495669.1 hypothetical protein -
CSC52_RS04125 784525..785502 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
CSC52_RS04130 785504..785824 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC52_RS04135 785976..786641 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106146 WP_001802298.1 NZ_CP029658:782631-782735 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106146 NZ_CP029658:782631-782735 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT106146 NZ_CP029658:c782893-782730 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References