Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1201981..1202243 Replicon chromosome
Accession NZ_CP029655
Organism Staphylococcus aureus strain AR_0469

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSC54_RS06240 Protein ID WP_001802298.1
Coordinates 1201981..1202085 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1202080..1202243 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC54_RS06215 1198778..1199560 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
CSC54_RS06220 1199628..1200485 + 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
CSC54_RS06230 1201143..1201301 - 159 WP_001792784.1 hypothetical protein -
CSC54_RS06240 1201981..1202085 + 105 WP_001802298.1 hypothetical protein Toxin
- 1202080..1202243 - 164 - - Antitoxin
CSC54_RS06245 1202518..1203609 - 1092 WP_000495669.1 hypothetical protein -
CSC54_RS06250 1203875..1204852 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
CSC54_RS06255 1204854..1205174 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC54_RS06260 1205326..1205991 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106114 WP_001802298.1 NZ_CP029655:1201981-1202085 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106114 NZ_CP029655:1201981-1202085 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT106114 NZ_CP029655:c1202243-1202080 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References