Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2361054..2361270 Replicon chromosome
Accession NZ_CP029653
Organism Staphylococcus aureus strain AR_0470

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag CSC55_RS12160 Protein ID WP_073392962.1
Coordinates 2361166..2361270 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2361054..2361109 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC55_RS12140 2357248..2357913 - 666 WP_001024099.1 SDR family oxidoreductase -
CSC55_RS12145 2358065..2358385 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC55_RS12150 2358387..2359367 + 981 WP_001573505.1 CDF family zinc efflux transporter CzrB -
CSC55_RS12155 2359633..2360724 + 1092 WP_000495684.1 hypothetical protein -
- 2361054..2361109 + 56 - - Antitoxin
CSC55_RS12160 2361166..2361270 - 105 WP_073392962.1 hypothetical protein Toxin
CSC55_RS12170 2361950..2362108 + 159 WP_001792784.1 hypothetical protein -
CSC55_RS12180 2362767..2363624 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
CSC55_RS12185 2363692..2364474 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T106103 WP_073392962.1 NZ_CP029653:c2361270-2361166 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106103 NZ_CP029653:c2361270-2361166 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT106103 NZ_CP029653:2361054-2361109 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References