Detailed information of TA system TA106093

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1066555..1066804
• Replicon: chromosome
• Accession: NZ_CP029653
• Organism: Staphylococcus aureus strain AR_0470

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: CSC55_RS05240
• Protein ID: WP_000623369.1
• Coordinates: 1066555..1066662 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1066657..1066804 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSC55_RS05215	1063228..1063797	-	570	WP_000287265.1	competence protein ComK	-
CSC55_RS05220	1064007..1064225	+	219	WP_000876825.1	IDEAL domain-containing protein	-
CSC55_RS05225	1064306..1065292	-	987	WP_000668820.1	lipoate--protein ligase	-
CSC55_RS05230	1065491..1065667	+	177	WP_000214898.1	YkvS family protein	-
CSC55_RS05235	1065682..1066284	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
CSC55_RS05240	1066555..1066662	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1066657..1066804	-	148	-	-	Antitoxin
CSC55_RS05245	1067201..1067302	+	102	WP_001790623.1	hypothetical protein	-
CSC55_RS05250	1067312..1067584	+	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
CSC55_RS05255	1067628..1069592	+	1965	WP_000870819.1	bacteriocin-associated integral membrane family protein	-
CSC55_RS05260	1069595..1069915	+	321	WP_000873929.1	YxeA family protein	-
CSC55_RS05265	1069912..1070553	+	642	WP_001574505.1	ABC transporter ATP-binding protein	-
CSC55_RS05270	1070641..1070931	-	291	WP_001791476.1	hypothetical protein	-
CSC55_RS05275	1071272..1071559	+	288	WP_000410718.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T106093 WP_000623369.1 NZ_CP029653:1066555-1066662 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T106093 NZ_CP029653:1066555-1066662 [Staphylococcus aureus]
GTGATATCTATTGCAAACGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT106093 NZ_CP029653:c1066804-1066657 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGGAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin