Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1991122..1991306 Replicon chromosome
Accession NZ_CP029652
Organism Staphylococcus aureus strain AR_0471

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CSC56_RS10230 Protein ID WP_000482647.1
Coordinates 1991122..1991229 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1991246..1991306 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC56_RS10205 1986486..1986959 + 474 WP_000456491.1 GyrI-like domain-containing protein -
CSC56_RS10210 1987082..1988293 - 1212 WP_001191975.1 multidrug effflux MFS transporter -
CSC56_RS10215 1988473..1989132 - 660 WP_000831298.1 membrane protein -
CSC56_RS10220 1989192..1990334 - 1143 WP_001176860.1 glycerate kinase -
CSC56_RS10225 1990602..1990988 + 387 WP_000779354.1 flippase GtxA -
CSC56_RS10230 1991122..1991229 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1991246..1991306 - 61 - - Antitoxin
CSC56_RS10235 1991801..1993540 + 1740 WP_001064831.1 ABC transporter ATP-binding protein/permease -
CSC56_RS10240 1993589..1995322 + 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
CSC56_RS10250 1995553..1995720 + 168 WP_031785511.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T106083 WP_000482647.1 NZ_CP029652:1991122-1991229 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106083 NZ_CP029652:1991122-1991229 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106083 NZ_CP029652:c1991306-1991246 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References