Detailed information of TA system TA106079

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2730552..2730732
• Replicon: chromosome
• Accession: NZ_CP029649
• Organism: Staphylococcus aureus strain AR_0472

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: CSC57_RS14245
• Protein ID: WP_001801861.1
• Coordinates: 2730637..2730732 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2730552..2730609 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSC57_RS14215	2726903..2728021	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
CSC57_RS14220	2728669..2729085	+	417	WP_020978241.1	DUF1433 domain-containing protein	-
CSC57_RS14225	2729322..2729669	+	348	WP_001566695.1	DUF1433 domain-containing protein	-
CSC57_RS14230	2729691..2730065	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
CSC57_RS14235	2730253..2730435	+	183	Protein_2637	transposase	-
CSC57_RS14240	2730413..2730514	-	102	WP_001791232.1	hypothetical protein	-
-	2730552..2730609	+	58	-	-	Antitoxin
CSC57_RS14245	2730637..2730732	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
CSC57_RS14255	2731183..2731629	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
CSC57_RS14260	2732314..2732697	+	384	WP_000070811.1	hypothetical protein	-
CSC57_RS14265	2732708..2732884	+	177	WP_000375476.1	hypothetical protein	-
CSC57_RS14275	2733255..2733812	+	558	WP_000864139.1	ImmA/IrrE family metallo-endopeptidase	-
CSC57_RS14280	2734010..2734582	-	573	WP_000414206.1	hypothetical protein	-
CSC57_RS14285	2734683..2735024	-	342	WP_000627547.1	DUF3969 family protein	-
CSC57_RS14290	2735065..2735691	-	627	WP_000669021.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hlgA / lukD	2692694..2738249	45555

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T106079 WP_001801861.1 NZ_CP029649:c2730732-2730637 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T106079 NZ_CP029649:c2730732-2730637 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT106079 NZ_CP029649:2730552-2730609 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin