Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2392748..2393010 Replicon chromosome
Accession NZ_CP029649
Organism Staphylococcus aureus strain AR_0472

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSC57_RS12160 Protein ID WP_001802298.1
Coordinates 2392748..2392852 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2392847..2393010 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC57_RS12135 2389545..2390327 + 783 WP_000908189.1 ABC transporter ATP-binding protein -
CSC57_RS12140 2390395..2391252 + 858 WP_000370928.1 Cof-type HAD-IIB family hydrolase -
CSC57_RS12150 2391910..2392068 - 159 WP_001792784.1 hypothetical protein -
CSC57_RS14815 2392061..2392231 - 171 WP_001792292.1 transposase -
CSC57_RS12160 2392748..2392852 + 105 WP_001802298.1 hypothetical protein Toxin
- 2392847..2393010 - 164 - - Antitoxin
CSC57_RS12165 2393351..2394442 - 1092 WP_000495681.1 hypothetical protein -
CSC57_RS12170 2394708..2395688 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
CSC57_RS12175 2395690..2396010 - 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC57_RS12180 2396162..2396827 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T106069 WP_001802298.1 NZ_CP029649:2392748-2392852 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T106069 NZ_CP029649:2392748-2392852 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT106069 NZ_CP029649:c2393010-2392847 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References