Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 2136298..2136815 | Replicon | chromosome |
Accession | NZ_CP029649 | ||
Organism | Staphylococcus aureus strain AR_0472 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | T1YC79 |
Locus tag | CSC57_RS10780 | Protein ID | WP_000113262.1 |
Coordinates | 2136549..2136815 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | T1YB60 |
Locus tag | CSC57_RS10775 | Protein ID | WP_000584499.1 |
Coordinates | 2136298..2136549 (+) | Length | 84 a.a. |
Genomic Context
Location: 2131996..2132715 (720 bp)
Type: Others
Protein ID: WP_000479576.1
Type: Others
Protein ID: WP_000479576.1
Location: 2132712..2133443 (732 bp)
Type: Others
Protein ID: WP_000615461.1
Type: Others
Protein ID: WP_000615461.1
Location: 2135045..2135407 (363 bp)
Type: Others
Protein ID: WP_000819843.1
Type: Others
Protein ID: WP_000819843.1
Location: 2135426..2136025 (600 bp)
Type: Others
Protein ID: WP_000162803.1
Type: Others
Protein ID: WP_000162803.1
Location: 2136032..2136133 (102 bp)
Type: Others
Protein ID: Protein_2026
Type: Others
Protein ID: Protein_2026
Location: 2136298..2136549 (252 bp)
Type: Antitoxin
Protein ID: WP_000584499.1
Type: Antitoxin
Protein ID: WP_000584499.1
Location: 2136549..2136815 (267 bp)
Type: Toxin
Protein ID: WP_000113262.1
Type: Toxin
Protein ID: WP_000113262.1
Location: 2137109..2138659 (1551 bp)
Type: Others
Protein ID: WP_000727763.1
Type: Others
Protein ID: WP_000727763.1
Location: 2138845..2139312 (468 bp)
Type: Others
Protein ID: WP_110179774.1
Type: Others
Protein ID: WP_110179774.1
Location: 2139399..2139581 (183 bp)
Type: Others
Protein ID: WP_000079142.1
Type: Others
Protein ID: WP_000079142.1
Location: 2139798..2140622 (825 bp)
Type: Others
Protein ID: WP_000572040.1
Type: Others
Protein ID: WP_000572040.1
Location: 2140856..2141392 (537 bp)
Type: Others
Protein ID: WP_000169317.1
Type: Others
Protein ID: WP_000169317.1
Location: 2133540..2134790 (1251 bp)
Type: Others
Protein ID: WP_001012228.1
Type: Others
Protein ID: WP_001012228.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CSC57_RS10745 | 2131996..2132715 | + | 720 | WP_000479576.1 | amino acid ABC transporter permease | - |
CSC57_RS10750 | 2132712..2133443 | + | 732 | WP_000615461.1 | amino acid ABC transporter ATP-binding protein | - |
CSC57_RS10755 | 2133540..2134790 | - | 1251 | WP_001012228.1 | FemA/FemB family glycyltransferase FmhA | - |
CSC57_RS10760 | 2135045..2135407 | + | 363 | WP_000819843.1 | DUF4467 domain-containing protein | - |
CSC57_RS10765 | 2135426..2136025 | + | 600 | WP_000162803.1 | DsbA family protein | - |
CSC57_RS10770 | 2136032..2136133 | + | 102 | Protein_2026 | hypothetical protein | - |
CSC57_RS10775 | 2136298..2136549 | + | 252 | WP_000584499.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
CSC57_RS10780 | 2136549..2136815 | + | 267 | WP_000113262.1 | Txe/YoeB family addiction module toxin | Toxin |
CSC57_RS10785 | 2137109..2138659 | + | 1551 | WP_000727763.1 | zinc ABC transporter substrate-binding lipoprotein AdcA | - |
CSC57_RS10790 | 2138845..2139312 | + | 468 | WP_110179774.1 | SRPBCC domain-containing protein | - |
CSC57_RS10795 | 2139399..2139581 | + | 183 | WP_000079142.1 | hypothetical protein | - |
CSC57_RS10800 | 2139798..2140622 | + | 825 | WP_000572040.1 | formate/nitrite transporter family protein | - |
CSC57_RS10805 | 2140856..2141392 | + | 537 | WP_000169317.1 | GNAT family N-acetyltransferase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10437.95 Da Isoelectric Point: 9.9143
>T106068 WP_000113262.1 NZ_CP029649:2136549-2136815 [Staphylococcus aureus]
MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
Download Length: 267 bp
>T106068 NZ_CP029649:2136549-2136815 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9433.60 Da Isoelectric Point: 4.3407
>AT106068 WP_000584499.1 NZ_CP029649:2136298-2136549 [Staphylococcus aureus]
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
Download Length: 252 bp
>AT106068 NZ_CP029649:2136298-2136549 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA