Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2492646..2492830 Replicon chromosome
Accession NZ_CP029629
Organism Staphylococcus aureus strain MOK063

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DLJ56_RS12985 Protein ID WP_000482647.1
Coordinates 2492723..2492830 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2492646..2492706 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ56_RS12960 2488100..2488267 - 168 WP_001790576.1 hypothetical protein -
DLJ56_RS12970 2488498..2490231 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DLJ56_RS12975 2490256..2492019 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2492646..2492706 + 61 - - Antitoxin
DLJ56_RS12985 2492723..2492830 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DLJ56_RS12990 2492964..2493350 - 387 WP_000779360.1 flippase GtxA -
DLJ56_RS12995 2493608..2494750 + 1143 WP_001176863.1 glycerate kinase -
DLJ56_RS13000 2494810..2495469 + 660 WP_000831298.1 membrane protein -
DLJ56_RS13005 2495651..2496862 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DLJ56_RS13010 2496985..2497458 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T106051 WP_000482647.1 NZ_CP029629:c2492830-2492723 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106051 NZ_CP029629:c2492830-2492723 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106051 NZ_CP029629:2492646-2492706 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References