Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2536501..2536685 Replicon chromosome
Accession NZ_CP029627
Organism Staphylococcus aureus strain MOK042

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DLJ55_RS13370 Protein ID WP_000482647.1
Coordinates 2536578..2536685 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2536501..2536561 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DLJ55_RS13345 2531955..2532122 - 168 WP_001790576.1 hypothetical protein -
DLJ55_RS13355 2532353..2534086 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
DLJ55_RS13360 2534111..2535874 - 1764 WP_001064814.1 ABC transporter ATP-binding protein/permease -
- 2536501..2536561 + 61 - - Antitoxin
DLJ55_RS13370 2536578..2536685 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DLJ55_RS13375 2536819..2537205 - 387 WP_000779360.1 flippase GtxA -
DLJ55_RS13380 2537463..2538605 + 1143 WP_001176863.1 glycerate kinase -
DLJ55_RS13385 2538665..2539324 + 660 WP_000831298.1 membrane protein -
DLJ55_RS13390 2539506..2540717 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DLJ55_RS13395 2540840..2541313 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 2512900..2539324 26424


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T106043 WP_000482647.1 NZ_CP029627:c2536685-2536578 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T106043 NZ_CP029627:c2536685-2536578 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT106043 NZ_CP029627:2536501-2536561 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References