106030

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 3021695..3022074 Replicon chromosome
Accession NZ_CP029612
Organism Enterococcus faecalis strain H25

Toxin (Protein)


Gene name txpA Uniprot ID E2Z0W4
Locus tag CNQ40_RS15940 Protein ID WP_002381035.1
Coordinates 3021931..3022074 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 3021695..3021758 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ40_RS15915 3017050..3017265 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
CNQ40_RS15920 3017404..3018396 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
CNQ40_RS15925 3018660..3019298 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
CNQ40_RS15935 3019983..3021599 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
- 3021695..3021758 - 64 - - Antitoxin
CNQ40_RS15940 3021931..3022074 + 144 WP_002381035.1 putative holin-like toxin Toxin
CNQ40_RS15945 3022269..3026855 - 4587 WP_010730419.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5202.20 Da        Isoelectric Point: 10.0041

>T106030 WP_002381035.1 NZ_CP029612:3021931-3022074 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

>T106030 NZ_CP029612:3021931-3022074 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 64 bp

>AT106030 NZ_CP029612:c3021758-3021695 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTGATGTAGAGCCGTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6BWH2

Antitoxin

Download structure file

References