Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 74462..74724 Replicon chromosome
Accession NZ_CP029474
Organism Staphylococcus aureus strain USA 100 isolate 30-47

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DKK89_RS00420 Protein ID WP_001802298.1
Coordinates 74620..74724 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 74462..74625 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DKK89_RS00400 70714..71379 - 666 WP_001024095.1 SDR family oxidoreductase -
DKK89_RS00405 71531..71851 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DKK89_RS00410 71853..72830 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
DKK89_RS00415 73096..74187 + 1092 WP_000495669.1 hypothetical protein -
- 74462..74625 + 164 - - Antitoxin
DKK89_RS00420 74620..74724 - 105 WP_001802298.1 hypothetical protein Toxin
DKK89_RS14360 75241..75411 + 171 WP_001792292.1 transposase -
DKK89_RS00430 75404..75562 + 159 WP_001792784.1 hypothetical protein -
DKK89_RS00440 76220..77077 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
DKK89_RS00445 77145..77927 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T105696 WP_001802298.1 NZ_CP029474:c74724-74620 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T105696 NZ_CP029474:c74724-74620 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT105696 NZ_CP029474:74462-74625 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References