Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 3076904..3077508 Replicon chromosome
Accession NZ_CP029275
Organism Xanthomonas citri strain M11

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag DGM98_RS13470 Protein ID WP_099802820.1
Coordinates 3077194..3077508 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag DGM98_RS13465 Protein ID WP_099802819.1
Coordinates 3076904..3077194 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DGM98_RS13445 (DGM98_14015) 3072121..3072531 - 411 WP_005914237.1 TcpQ domain-containing protein -
DGM98_RS13450 (DGM98_14020) 3072865..3074538 - 1674 WP_089095178.1 type IV secretory system conjugative DNA transfer family protein -
DGM98_RS13455 (DGM98_14025) 3074575..3074817 - 243 WP_022559483.1 hypothetical protein -
DGM98_RS13460 (DGM98_14030) 3075683..3076912 + 1230 WP_158526043.1 site-specific integrase -
DGM98_RS13465 (DGM98_14035) 3076904..3077194 - 291 WP_099802819.1 NadS family protein Antitoxin
DGM98_RS13470 (DGM98_14040) 3077194..3077508 - 315 WP_099802820.1 hypothetical protein Toxin
DGM98_RS13475 (DGM98_14045) 3077961..3078590 - 630 WP_145958286.1 hypothetical protein -
DGM98_RS13480 3078667..3078858 + 192 WP_193588907.1 helix-turn-helix domain-containing protein -
DGM98_RS13485 (DGM98_14055) 3078855..3079052 + 198 WP_099801965.1 hypothetical protein -
DGM98_RS13490 (DGM98_14060) 3079136..3079477 + 342 WP_099801966.1 hypothetical protein -
DGM98_RS13495 (DGM98_14065) 3079474..3079677 + 204 WP_099801967.1 hypothetical protein -
DGM98_RS13500 (DGM98_14070) 3079674..3079853 + 180 WP_099801968.1 hypothetical protein -
DGM98_RS13505 (DGM98_14075) 3079850..3080116 + 267 WP_099801969.1 hypothetical protein -
DGM98_RS13510 (DGM98_14080) 3080109..3080456 + 348 WP_099801970.1 hypothetical protein -
DGM98_RS13515 (DGM98_14085) 3080588..3080947 + 360 WP_099863717.1 helix-turn-helix domain-containing protein -
DGM98_RS13520 (DGM98_14090) 3081183..3081464 + 282 WP_099801972.1 hypothetical protein -
DGM98_RS13525 (DGM98_14095) 3081461..3081787 + 327 WP_145958287.1 hypothetical protein -
DGM98_RS13530 (DGM98_14100) 3081784..3082038 + 255 WP_145958288.1 hypothetical protein -
DGM98_RS13535 (DGM98_14105) 3082156..3082464 + 309 WP_145958289.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3066310..3097138 30828


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-87)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11650.49 Da        Isoelectric Point: 9.3988

>T105383 WP_099802820.1 NZ_CP029275:c3077508-3077194 [Xanthomonas citri]
MIFVETPIFTASVTELLTDEQYGAFQSFLIAEPRAGDVIEQTGGLRKVRWSVAGKGKRGGVRVIYYFVDEADQIRLLLIY
KKGVQDDLTPSQKKVLKAIKDGWA

Download         Length: 315 bp

>T105383 NZ_CP029275:c3077508-3077194 [Xanthomonas citri]
ATGATCTTCGTCGAGACCCCCATCTTCACTGCCTCGGTGACAGAGCTTTTGACCGATGAGCAGTACGGGGCGTTTCAGTC
ATTCCTGATCGCGGAGCCGCGCGCCGGCGACGTCATCGAGCAGACGGGCGGCCTGCGTAAGGTGCGCTGGTCTGTAGCGG
GGAAGGGCAAGCGCGGCGGGGTCAGGGTTATCTACTACTTCGTGGATGAGGCCGATCAGATCCGGCTGCTGCTGATCTAC
AAAAAGGGCGTGCAGGACGACCTGACGCCGTCCCAGAAGAAAGTGCTGAAAGCAATCAAAGACGGGTGGGCATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10638.24 Da        Isoelectric Point: 10.7495

>AT105383 WP_099802819.1 NZ_CP029275:c3077194-3076904 [Xanthomonas citri]
MDKNLFAQLAESMEQMGEITRGERAPSREIHIDAVRVKEVRAATGLSQAKFAQVIDVQLGTLRNWEQGRRNPTGPARALL
RAIKKDPKSVLEALSA

Download         Length: 291 bp

>AT105383 NZ_CP029275:c3077194-3076904 [Xanthomonas citri]
ATGGACAAGAATCTCTTCGCACAACTCGCCGAGAGCATGGAACAGATGGGCGAGATCACTCGCGGCGAACGGGCTCCGTC
TCGCGAGATCCACATCGATGCCGTGCGGGTGAAAGAGGTCCGGGCCGCCACTGGGCTGTCACAGGCGAAATTCGCTCAGG
TGATCGACGTGCAGCTCGGCACCTTGCGTAATTGGGAGCAGGGGCGGCGGAACCCTACGGGGCCTGCCCGAGCGCTGCTG
CGTGCGATCAAGAAGGATCCCAAGAGCGTGCTGGAAGCTCTGTCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References