Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 79466..80123 | Replicon | plasmid p846 |
| Accession | NZ_CP029249 | ||
| Organism | Salmonella enterica subsp. enterica serovar Thompson strain HFCDC-SM-846 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | DBR05_RS24775 | Protein ID | WP_000270043.1 |
| Coordinates | 79466..79816 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | DBR05_RS24780 | Protein ID | WP_000124640.1 |
| Coordinates | 79821..80123 (+) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DBR05_RS24725 | 74777..74956 | + | 180 | Protein_78 | helix-turn-helix transcriptional regulator | - |
| DBR05_RS24730 | 75021..75725 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| DBR05_RS24735 | 75940..76437 | - | 498 | WP_000062185.1 | hypothetical protein | - |
| DBR05_RS24740 | 76440..76928 | - | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| DBR05_RS24745 | 77025..77360 | + | 336 | WP_000683476.1 | hypothetical protein | - |
| DBR05_RS24750 | 77375..77845 | - | 471 | WP_001281821.1 | hypothetical protein | - |
| DBR05_RS24755 | 77838..78209 | - | 372 | WP_000516916.1 | hypothetical protein | - |
| DBR05_RS24760 | 78220..78414 | - | 195 | WP_000343597.1 | hypothetical protein | - |
| DBR05_RS24770 | 78755..79303 | - | 549 | WP_001061574.1 | transcriptional regulator | - |
| DBR05_RS24775 | 79466..79816 | + | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| DBR05_RS24780 | 79821..80123 | + | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| DBR05_RS24785 | 80150..80443 | - | 294 | WP_001239997.1 | chromosome segregation protein ParM | - |
| DBR05_RS24790 | 80531..80803 | - | 273 | WP_001043047.1 | HU family DNA-binding protein | - |
| DBR05_RS24795 | 80861..81388 | - | 528 | WP_001236377.1 | thermonuclease family protein | - |
| DBR05_RS24805 | 81619..82476 | - | 858 | WP_001167032.1 | hypothetical protein | - |
| DBR05_RS24810 | 82463..82693 | - | 231 | WP_000972663.1 | hypothetical protein | - |
| DBR05_RS24815 | 82693..83211 | - | 519 | WP_000210756.1 | nitrite reductase | - |
| DBR05_RS24820 | 83208..83654 | - | 447 | WP_000919345.1 | Fe3+-siderophore ABC transporter permease | - |
| DBR05_RS24825 | 83654..84013 | - | 360 | WP_000422768.1 | hypothetical protein | - |
| DBR05_RS24830 | 84070..84498 | - | 429 | WP_000591074.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..152940 | 152940 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T105360 WP_000270043.1 NZ_CP029249:79466-79816 [Salmonella enterica subsp. enterica serovar Thompson]
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Download Length: 351 bp
>T105360 NZ_CP029249:79466-79816 [Salmonella enterica subsp. enterica serovar Thompson]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 12963.60 Da Isoelectric Point: 12.8000
>AT105360 WP_000124640.1 NZ_CP029249:79821-80123 [Salmonella enterica subsp. enterica serovar Thompson]
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Download Length: 303 bp
>AT105360 NZ_CP029249:79821-80123 [Salmonella enterica subsp. enterica serovar Thompson]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|