Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 2586323..2586507 | Replicon | chromosome |
Accession | NZ_CP029172 | ||
Organism | Staphylococcus aureus strain PTDrAP2 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2P7CQJ7 |
Locus tag | DD562_RS13395 | Protein ID | WP_000482647.1 |
Coordinates | 2586400..2586507 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 2586323..2586383 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
DD562_RS13370 | 2581777..2581944 | - | 168 | WP_001798790.1 | hypothetical protein | - |
DD562_RS13380 | 2582175..2583908 | - | 1734 | WP_000486511.1 | ABC transporter ATP-binding protein/permease | - |
DD562_RS13385 | 2583933..2585696 | - | 1764 | WP_001064818.1 | ABC transporter ATP-binding protein/permease | - |
- | 2586323..2586383 | + | 61 | - | - | Antitoxin |
DD562_RS13395 | 2586400..2586507 | - | 108 | WP_000482647.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
DD562_RS13400 | 2586641..2587027 | - | 387 | WP_000779355.1 | flippase GtxA | - |
DD562_RS13405 | 2587294..2588436 | + | 1143 | WP_001176859.1 | glycerate kinase | - |
DD562_RS13410 | 2588496..2589155 | + | 660 | WP_000831300.1 | hypothetical protein | - |
DD562_RS13415 | 2589343..2590554 | + | 1212 | WP_001191974.1 | multidrug effflux MFS transporter | - |
DD562_RS13420 | 2590677..2591150 | - | 474 | WP_000456489.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4012.76 Da Isoelectric Point: 10.4935
>T105141 WP_000482647.1 NZ_CP029172:c2586507-2586400 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T105141 NZ_CP029172:c2586507-2586400 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 61 bp
>AT105141 NZ_CP029172:2586323-2586383 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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