Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2586323..2586507 Replicon chromosome
Accession NZ_CP029172
Organism Staphylococcus aureus strain PTDrAP2

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag DD562_RS13395 Protein ID WP_000482647.1
Coordinates 2586400..2586507 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2586323..2586383 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD562_RS13370 2581777..2581944 - 168 WP_001798790.1 hypothetical protein -
DD562_RS13380 2582175..2583908 - 1734 WP_000486511.1 ABC transporter ATP-binding protein/permease -
DD562_RS13385 2583933..2585696 - 1764 WP_001064818.1 ABC transporter ATP-binding protein/permease -
- 2586323..2586383 + 61 - - Antitoxin
DD562_RS13395 2586400..2586507 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
DD562_RS13400 2586641..2587027 - 387 WP_000779355.1 flippase GtxA -
DD562_RS13405 2587294..2588436 + 1143 WP_001176859.1 glycerate kinase -
DD562_RS13410 2588496..2589155 + 660 WP_000831300.1 hypothetical protein -
DD562_RS13415 2589343..2590554 + 1212 WP_001191974.1 multidrug effflux MFS transporter -
DD562_RS13420 2590677..2591150 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T105141 WP_000482647.1 NZ_CP029172:c2586507-2586400 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T105141 NZ_CP029172:c2586507-2586400 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT105141 NZ_CP029172:2586323-2586383 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References