Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2290639..2290902 Replicon chromosome
Accession NZ_CP029172
Organism Staphylococcus aureus strain PTDrAP2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag DD562_RS11775 Protein ID WP_001802298.1
Coordinates 2290798..2290902 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2290639..2290803 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD562_RS11755 2286824..2287489 - 666 WP_001024099.1 SDR family oxidoreductase -
DD562_RS11760 2287641..2287961 + 321 WP_109028251.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
DD562_RS11765 2287963..2288943 + 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
DD562_RS11770 2289209..2290300 + 1092 WP_000495673.1 hypothetical protein -
- 2290639..2290803 + 165 - - Antitoxin
DD562_RS11775 2290798..2290902 - 105 WP_001802298.1 hypothetical protein Toxin
DD562_RS11790 2291582..2291740 + 159 WP_001792784.1 hypothetical protein -
DD562_RS11800 2292398..2293255 - 858 WP_000370942.1 Cof-type HAD-IIB family hydrolase -
DD562_RS11805 2293323..2294105 - 783 WP_000908191.1 ABC transporter ATP-binding protein -
DD562_RS11810 2294395..2295003 - 609 WP_109028252.1 TIR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T105139 WP_001802298.1 NZ_CP029172:c2290902-2290798 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T105139 NZ_CP029172:c2290902-2290798 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT105139 NZ_CP029172:2290639-2290803 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References