Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2596589..2596773 Replicon chromosome
Accession NZ_CP029166
Organism Staphylococcus aureus strain SVH7513

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag DD555_RS13795 Protein ID WP_000482650.1
Coordinates 2596666..2596773 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2596589..2596649 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD555_RS13770 2592119..2592286 - 168 WP_001789936.1 hypothetical protein -
DD555_RS13780 2592517..2594250 - 1734 WP_084927537.1 ABC transporter ATP-binding protein/permease -
DD555_RS13785 2594275..2596038 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2596589..2596649 + 61 - - Antitoxin
DD555_RS13795 2596666..2596773 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
DD555_RS13800 2596907..2597293 - 387 WP_000779358.1 flippase GtxA -
DD555_RS13805 2597561..2598703 + 1143 WP_001176863.1 glycerate kinase -
DD555_RS13810 2598763..2599422 + 660 WP_000831298.1 membrane protein -
DD555_RS13815 2599604..2600815 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
DD555_RS13820 2600938..2601411 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T105127 WP_000482650.1 NZ_CP029166:c2596773-2596666 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T105127 NZ_CP029166:c2596773-2596666 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT105127 NZ_CP029166:2596589-2596649 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References