Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 491625..492275 Replicon chromosome
Accession NZ_CP029150
Organism Glaesserella parasuis strain GZ20170512

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C3363_RS02420 Protein ID WP_010786052.1
Coordinates 491937..492275 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C3363_RS02415 Protein ID WP_005710405.1
Coordinates 491625..491933 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C3363_RS02390 486943..487422 - 480 WP_010786058.1 transcription elongation factor GreB -
C3363_RS02395 487422..488357 - 936 WP_010786057.1 KpsF/GutQ family sugar-phosphate isomerase -
C3363_RS02400 488419..489000 - 582 WP_010786056.1 type IV pilus biogenesis/stability protein PilW -
C3363_RS02405 489247..490220 + 974 Protein_449 transposase -
C3363_RS02410 490264..491424 - 1161 WP_010786053.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
C3363_RS02415 491625..491933 - 309 WP_005710405.1 helix-turn-helix domain-containing protein Antitoxin
C3363_RS02420 491937..492275 - 339 WP_010786052.1 hypothetical protein Toxin
C3363_RS02445 493109..494548 + 1440 WP_010786051.1 glutamate--tRNA ligase -
C3363_RS02455 495031..497079 - 2049 Protein_454 cadmium-translocating P-type ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-86)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13259.31 Da        Isoelectric Point: 9.8649

>T105048 WP_010786052.1 NZ_CP029150:c492275-491937 [Glaesserella parasuis]
MNVTFVELPPFEEYRKKYLDDDTFRLLQNELLKFPDKGELIQGTGGLRKLRIVDIIRQKGKRGGARVIYYYYVRGKQVWL
FHAYNKNQQDDLSNEELVVLANTLSYLKSLVR

Download         Length: 339 bp

>T105048 NZ_CP029150:c492275-491937 [Glaesserella parasuis]
ATGAATGTCACTTTTGTGGAATTACCGCCTTTTGAGGAATATAGAAAAAAGTATCTTGACGATGACACATTTAGATTATT
ACAAAATGAGTTATTAAAATTTCCCGATAAGGGAGAGCTTATTCAAGGTACTGGGGGACTAAGAAAATTGCGTATTGTAG
ATATTATTAGACAAAAAGGAAAAAGAGGCGGAGCTAGGGTAATCTATTACTATTACGTGCGAGGGAAACAAGTTTGGTTG
TTCCACGCCTACAATAAAAACCAACAAGACGATTTATCTAATGAAGAACTTGTGGTTTTGGCGAATACATTAAGCTATTT
AAAATCTTTAGTGAGGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11539.61 Da        Isoelectric Point: 10.2919

>AT105048 WP_005710405.1 NZ_CP029150:c491933-491625 [Glaesserella parasuis]
MGKLFNELMEGMQALELHLQGKITLKTTVVEVPDPIVITPEEVKAIRQKLNLSQAVFARKLHTSVRTYQGWEQGRTKPNP
QAVLLLKMVEKSPKTFEQIASI

Download         Length: 309 bp

>AT105048 NZ_CP029150:c491933-491625 [Glaesserella parasuis]
ATGGGAAAATTATTTAATGAACTAATGGAAGGGATGCAAGCATTAGAGTTACACTTACAAGGCAAAATTACACTAAAAAC
CACTGTTGTGGAAGTTCCTGATCCGATAGTGATTACCCCCGAAGAAGTGAAAGCTATTCGCCAAAAATTAAATCTTTCAC
AAGCGGTTTTTGCTCGTAAATTACACACTTCGGTGAGAACTTATCAAGGTTGGGAGCAAGGAAGAACAAAGCCCAATCCG
CAAGCGGTCTTACTATTAAAAATGGTTGAAAAATCGCCAAAAACATTTGAGCAAATTGCGAGCATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References