Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 1021573..1021757 | Replicon | chromosome |
Accession | NZ_CP029086 | ||
Organism | Staphylococcus aureus strain AR462 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | A0A2U0ISP5 |
Locus tag | CSC48_RS05660 | Protein ID | WP_000482652.1 |
Coordinates | 1021650..1021757 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 1021573..1021633 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CSC48_RS05635 | 1017028..1017195 | - | 168 | Protein_992 | hypothetical protein | - |
CSC48_RS05645 | 1017426..1019159 | - | 1734 | WP_000486487.1 | ABC transporter ATP-binding protein/permease | - |
CSC48_RS05650 | 1019184..1020947 | - | 1764 | WP_001064825.1 | ABC transporter ATP-binding protein/permease | - |
- | 1021573..1021633 | + | 61 | - | - | Antitoxin |
CSC48_RS05660 | 1021650..1021757 | - | 108 | WP_000482652.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
CSC48_RS05665 | 1021891..1022277 | - | 387 | WP_000779360.1 | flippase GtxA | - |
CSC48_RS05670 | 1022545..1023687 | + | 1143 | WP_001176863.1 | glycerate kinase | - |
CSC48_RS05675 | 1023747..1024406 | + | 660 | WP_000831298.1 | membrane protein | - |
CSC48_RS05680 | 1024588..1025799 | + | 1212 | WP_001192075.1 | multidrug effflux MFS transporter | - |
CSC48_RS05685 | 1025922..1026395 | - | 474 | WP_000456486.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4011.78 Da Isoelectric Point: 11.0582
>T104796 WP_000482652.1 NZ_CP029086:c1021757-1021650 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T104796 NZ_CP029086:c1021757-1021650 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 61 bp
>AT104796 NZ_CP029086:1021573-1021633 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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