104796

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1021573..1021757 Replicon chromosome
Accession NZ_CP029086
Organism Staphylococcus aureus strain AR462

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag CSC48_RS05660 Protein ID WP_000482652.1
Coordinates 1021650..1021757 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1021573..1021633 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC48_RS05635 1017028..1017195 - 168 Protein_992 hypothetical protein -
CSC48_RS05645 1017426..1019159 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
CSC48_RS05650 1019184..1020947 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 1021573..1021633 + 61 - - Antitoxin
CSC48_RS05660 1021650..1021757 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
CSC48_RS05665 1021891..1022277 - 387 WP_000779360.1 flippase GtxA -
CSC48_RS05670 1022545..1023687 + 1143 WP_001176863.1 glycerate kinase -
CSC48_RS05675 1023747..1024406 + 660 WP_000831298.1 membrane protein -
CSC48_RS05680 1024588..1025799 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
CSC48_RS05685 1025922..1026395 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T104796 WP_000482652.1 NZ_CP029086:c1021757-1021650 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T104796 NZ_CP029086:c1021757-1021650 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT104796 NZ_CP029086:1021573-1021633 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5


Antitoxin

Download structure file

References