104778

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 387294..387478 Replicon chromosome
Accession NZ_CP029084
Organism Staphylococcus aureus strain AR464

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag CSC49_RS02200 Protein ID WP_000482647.1
Coordinates 387371..387478 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 387294..387354 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC49_RS02180 382880..383047 - 168 WP_031785511.1 hypothetical protein -
CSC49_RS02190 383278..385011 - 1734 WP_000488492.1 ABC transporter ATP-binding protein/permease -
CSC49_RS02195 385060..386799 - 1740 WP_001064831.1 ABC transporter ATP-binding protein/permease -
- 387294..387354 + 61 - - Antitoxin
CSC49_RS02200 387371..387478 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
CSC49_RS02205 387612..387998 - 387 WP_000779354.1 flippase GtxA -
CSC49_RS02210 388266..389408 + 1143 WP_001176860.1 glycerate kinase -
CSC49_RS02215 389468..390127 + 660 WP_000831298.1 membrane protein -
CSC49_RS02220 390307..391518 + 1212 WP_001191975.1 multidrug effflux MFS transporter -
CSC49_RS02225 391641..392114 - 474 WP_000456491.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T104778 WP_000482647.1 NZ_CP029084:c387478-387371 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T104778 NZ_CP029084:c387478-387371 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT104778 NZ_CP029084:387294-387354 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References