Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1533387..1533665 Replicon chromosome
Accession NZ_CP029082
Organism Staphylococcus aureus strain AR465

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag CSC50_RS08090 Protein ID WP_001802298.1
Coordinates 1533387..1533491 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1533487..1533665 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC50_RS08065 1530184..1530966 + 783 WP_000908182.1 ABC transporter ATP-binding protein -
CSC50_RS08070 1531034..1531891 + 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
CSC50_RS08080 1532549..1532707 - 159 WP_001792784.1 hypothetical protein -
CSC50_RS08090 1533387..1533491 + 105 WP_001802298.1 hypothetical protein Toxin
- 1533487..1533665 - 179 - - Antitoxin
CSC50_RS08095 1533924..1535015 - 1092 WP_000495669.1 hypothetical protein -
CSC50_RS08100 1535281..1536258 - 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
CSC50_RS08105 1536260..1536580 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
CSC50_RS08110 1536732..1537397 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T104762 WP_001802298.1 NZ_CP029082:1533387-1533491 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T104762 NZ_CP029082:1533387-1533491 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT104762 NZ_CP029082:c1533665-1533487 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References