Detailed information of TA system TA104748

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 145100..145284
• Replicon: chromosome
• Accession: NZ_CP029080
• Organism: Staphylococcus aureus strain AR466

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: CSC51_RS00910
• Protein ID: WP_000482647.1
• Coordinates: 145177..145284 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	145100..145160 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSC51_RS00890	140686..140853	-	168	WP_031785511.1	hypothetical protein	-
CSC51_RS00900	141084..142817	-	1734	WP_000488492.1	ABC transporter ATP-binding protein/permease	-
CSC51_RS00905	142866..144605	-	1740	WP_001064831.1	ABC transporter ATP-binding protein/permease	-
CSC51_RS14460	144983..145150	-	168	WP_000301894.1	hypothetical protein	-
-	145100..145160	+	61	-	-	Antitoxin
CSC51_RS00910	145177..145284	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
CSC51_RS00915	145418..145804	-	387	WP_000779354.1	flippase GtxA	-
CSC51_RS00920	146072..147214	+	1143	WP_001176860.1	glycerate kinase	-
CSC51_RS00925	147274..147933	+	660	WP_000831298.1	membrane protein	-
CSC51_RS00930	148113..149324	+	1212	WP_001191975.1	multidrug effflux MFS transporter	-
CSC51_RS00935	149447..149920	-	474	WP_000456491.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T104748 WP_000482647.1 NZ_CP029080:c145284-145177 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T104748 NZ_CP029080:c145284-145177 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT104748 NZ_CP029080:145100-145160 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin