104377

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4123832..4125104 Replicon chromosome
Accession NZ_CP028923
Organism Roseivirga pacifica strain 9dcg1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag DCC35_RS18080 Protein ID WP_137092125.1
Coordinates 4124157..4125104 (+) Length 316 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag DCC35_RS18075 Protein ID WP_137092124.1
Coordinates 4123832..4124167 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DCC35_RS18045 4118938..4119294 + 357 WP_137092118.1 thioredoxin -
DCC35_RS18050 4119505..4121478 + 1974 WP_137092119.1 DUF2075 domain-containing protein -
DCC35_RS18055 4121590..4122075 + 486 WP_137092120.1 hypothetical protein -
DCC35_RS18060 4122115..4122708 + 594 WP_137092121.1 hypothetical protein -
DCC35_RS18065 4122731..4123258 + 528 WP_137092122.1 TPM domain-containing protein -
DCC35_RS18070 4123626..4123835 + 210 WP_137092123.1 helix-turn-helix transcriptional regulator -
DCC35_RS18075 4123832..4124167 + 336 WP_137092124.1 HipA N-terminal domain-containing protein Antitoxin
DCC35_RS18080 4124157..4125104 + 948 WP_137092125.1 HipA domain-containing protein Toxin
DCC35_RS18085 4125317..4126369 - 1053 WP_137092126.1 FAD-dependent oxidoreductase -
DCC35_RS18090 4126670..4127344 + 675 WP_137092127.1 hypothetical protein -
DCC35_RS18095 4127379..4128635 + 1257 WP_137092128.1 hypothetical protein -
DCC35_RS18100 4129028..4129210 + 183 WP_137092129.1 hypothetical protein -
DCC35_RS18105 4129329..4129805 + 477 WP_137092130.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(55-279)

Antitoxin

HipA, N-terminal subdomain 1

(4-102)


Sequences

Toxin        


Download         Length: 316 a.a.        Molecular weight: 35996.68 Da        Isoelectric Point: 8.9276

>T104377 WP_137092125.1 NZ_CP028923:4124157-4125104 [Roseivirga pacifica]
MENRCLYCYEPIKDEHDFHEKCSMVFFGTPTPPEIEYSINQMDELAKKVVERSVAVPGVQAKLSMSIVKETKGKSDTRLT
VVGALDGQYIFKPPSDKFPEMPENVHVTMRIAESFGIRVVLSSLCRLASGELSYITKRVDRTDTGSKIHMLDMFQITEAF
DKYKSSMEKVGKALGQYSSNTLLDKTFYFDLAIFSFLTGNNDMHLKNFSMIEGPSGRVLSPAYDLLNVGIIFPEDTEELA
LTLVRKKKKLKKEHFEKLGNELGLTPKQVKGSFNRMIKNKSKAFEWINRSFLSKEMKTAYKELLEKRYTQLGLQE

Download         Length: 948 bp

>T104377 NZ_CP028923:4124157-4125104 [Roseivirga pacifica]
ATGGAAAATAGATGTTTATATTGTTACGAACCTATTAAAGACGAACATGACTTTCATGAGAAATGTTCCATGGTATTCTT
TGGAACACCAACTCCTCCGGAAATTGAATATTCCATTAATCAAATGGATGAACTTGCTAAAAAAGTAGTTGAACGAAGTG
TAGCTGTTCCTGGTGTTCAGGCAAAACTGTCAATGTCCATCGTCAAAGAAACCAAAGGAAAATCTGACACAAGGTTAACT
GTGGTTGGGGCATTGGATGGACAATATATATTTAAACCCCCTTCTGACAAATTTCCCGAAATGCCAGAAAACGTACATGT
AACCATGCGAATTGCAGAATCTTTTGGAATCCGGGTAGTCCTATCATCATTGTGTCGATTAGCATCAGGAGAACTTTCAT
ATATAACGAAACGAGTTGATCGAACAGATACTGGTTCTAAGATTCACATGCTCGATATGTTTCAAATCACAGAGGCATTT
GATAAATACAAAAGTTCTATGGAGAAAGTTGGAAAAGCACTAGGTCAATATTCAAGCAACACGTTACTTGACAAAACTTT
TTACTTTGATCTGGCTATTTTTTCTTTTTTAACCGGGAATAACGATATGCACCTGAAAAACTTCTCAATGATCGAAGGTC
CTTCAGGACGGGTGTTATCCCCTGCTTATGATTTGTTAAATGTCGGTATAATCTTCCCGGAAGACACAGAAGAACTTGCG
CTGACACTGGTTAGAAAGAAAAAAAAGCTTAAGAAGGAACACTTTGAAAAATTGGGGAATGAACTTGGATTGACTCCTAA
ACAGGTCAAAGGAAGCTTTAATAGAATGATAAAAAATAAATCAAAAGCATTCGAATGGATCAACCGATCATTCCTTTCAA
AGGAAATGAAAACAGCCTATAAAGAATTACTAGAAAAAAGGTATACCCAATTGGGACTACAAGAATAG

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12912.68 Da        Isoelectric Point: 4.2530

>AT104377 WP_137092124.1 NZ_CP028923:4123832-4124167 [Roseivirga pacifica]
MRQGKVFYKDYLAGIITETDDGEYVFQYDEEYVKDHPDEFITFTMPVTTKPYTEKRLFPFFEGLIPEGWLLEIASENWKI
NKNDRMGLLLACCQNCIGAVSVKPIEEEDGK

Download         Length: 336 bp

>AT104377 NZ_CP028923:4123832-4124167 [Roseivirga pacifica]
ATGAGACAGGGCAAAGTATTTTATAAAGATTATTTAGCTGGTATCATTACAGAAACGGATGATGGTGAATATGTATTTCA
GTATGATGAAGAGTACGTAAAAGATCATCCAGATGAATTCATCACCTTTACAATGCCGGTAACAACAAAACCTTATACCG
AAAAAAGACTTTTTCCATTTTTTGAAGGATTGATTCCAGAAGGATGGTTATTAGAAATTGCTTCAGAAAACTGGAAAATT
AATAAAAATGACCGTATGGGATTACTACTTGCTTGTTGTCAAAATTGTATTGGTGCAGTGAGTGTCAAACCTATTGAAGA
GGAAGATGGAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References