Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 3802175..3802703 Replicon chromosome
Accession NZ_CP028766
Organism Escherichia coli strain A8

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag AOY61_RS18545 Protein ID WP_005080041.1
Coordinates 3802175..3802405 (+) Length 77 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag AOY61_RS18550 Protein ID WP_096979572.1
Coordinates 3802395..3802703 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3766477..3834975 68498


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(5-70)

Antitoxin

Cro/C1-type helix-turn-helix domain

(44-97)


Sequences

Toxin        


Download         Length: 77 a.a.        Molecular weight: 8682.15 Da        Isoelectric Point: 10.5308

>T103952 WP_005080041.1 NZ_CP028766:3802175-3802405 [Escherichia coli]
MKVYGSNLGEPHTSAFGDGLFELRIKGSDGIARVFYCTLTGKRIIMLHSFIKKTQKTPPAERKKAETRMKEVKHDW

Download         Length: 231 bp

>T103952 NZ_CP028766:3802175-3802405 [Escherichia coli]
ATGAAAGTATACGGCAGCAACCTCGGAGAACCTCATACCAGCGCCTTCGGTGACGGACTTTTCGAGCTTCGGATTAAAGG
CAGTGATGGCATCGCACGCGTCTTTTACTGCACTCTGACAGGAAAACGCATCATCATGCTGCACAGTTTCATCAAGAAGA
CTCAGAAAACCCCACCGGCTGAACGCAAAAAAGCTGAAACCAGAATGAAGGAGGTTAAGCATGACTGGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11170.84 Da        Isoelectric Point: 8.5840

>AT103952 WP_096979572.1 NZ_CP028766:3802395-3802703 [Escherichia coli]
MTGKRNPPTMTHDEMAAKWMDDPAFKAEYDAIADEFALLDEMLAARKEAGLTQAEVAERMGTKATAITRMESNLASGVSG
PSFSTLKKFARATGKKLQIRFV

Download         Length: 309 bp

>AT103952 NZ_CP028766:3802395-3802703 [Escherichia coli]
ATGACTGGTAAACGTAATCCGCCAACCATGACACACGATGAAATGGCAGCTAAATGGATGGATGACCCGGCTTTTAAAGC
AGAATACGACGCCATCGCCGACGAGTTCGCACTGCTTGATGAAATGCTGGCCGCACGCAAAGAAGCTGGTCTCACCCAGG
CTGAAGTTGCTGAACGCATGGGAACTAAAGCAACTGCCATCACCAGAATGGAAAGCAATCTTGCCTCTGGTGTCAGTGGG
CCATCATTTTCCACACTGAAAAAATTTGCACGCGCGACCGGGAAAAAACTCCAAATCCGCTTCGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References