Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 230353..230575 Replicon chromosome
Accession NZ_CP028734
Organism Escherichia coli strain A42

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag AOY95_RS01085 Protein ID WP_001295224.1
Coordinates 230468..230575 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 230353..230419 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOY95_RS01060 225741..226724 + 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
AOY95_RS01065 226721..227725 + 1005 WP_001525880.1 dipeptide ABC transporter ATP-binding subunit DppF -
AOY95_RS01070 227755..229026 - 1272 WP_001525879.1 aromatic amino acid transport family protein -
AOY95_RS01075 229502..229609 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein -
AOY95_RS01080 229985..230092 + 108 WP_000170748.1 type I toxin-antitoxin system toxin Ldr family protein -
- 230353..230419 - 67 - - Antitoxin
AOY95_RS01085 230468..230575 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
AOY95_RS01090 230661..232340 - 1680 WP_022296260.1 cellulose biosynthesis protein BcsG -
AOY95_RS01095 232337..232528 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
AOY95_RS01100 232525..234096 - 1572 WP_001204941.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
AOY95_RS01105 234369..234557 + 189 WP_001525878.1 cellulose biosynthesis protein BcsR -
AOY95_RS01110 234569..235321 + 753 WP_000279528.1 cellulose biosynthesis protein BcsQ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T103151 WP_001295224.1 NZ_CP028734:230468-230575 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T103151 NZ_CP028734:230468-230575 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT103151 NZ_CP028734:c230419-230353 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7


Antitoxin

Download structure file

References