Detailed information of TA system TA103149

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 229870..230092
• Replicon: chromosome
• Accession: NZ_CP028734
• Organism: Escherichia coli strain A42

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A3K0NFU8
• Locus tag: AOY95_RS01080
• Protein ID: WP_000170748.1
• Coordinates: 229985..230092 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	229870..229928 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOY95_RS01060	225741..226724	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
AOY95_RS01065	226721..227725	+	1005	WP_001525880.1	dipeptide ABC transporter ATP-binding subunit DppF	-
AOY95_RS01070	227755..229026	-	1272	WP_001525879.1	aromatic amino acid transport family protein	-
AOY95_RS01075	229502..229609	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	229870..229928	-	59	-	-	Antitoxin
AOY95_RS01080	229985..230092	+	108	WP_000170748.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
AOY95_RS01085	230468..230575	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
AOY95_RS01090	230661..232340	-	1680	WP_022296260.1	cellulose biosynthesis protein BcsG	-
AOY95_RS01095	232337..232528	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
AOY95_RS01100	232525..234096	-	1572	WP_001204941.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
AOY95_RS01105	234369..234557	+	189	WP_001525878.1	cellulose biosynthesis protein BcsR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3913.76 Da
• Isoelectric Point: 9.0157

>T103149 WP_000170748.1 NZ_CP028734:229985-230092 [Escherichia coli]
MTLAELGMAFWHDLAVPVITGILASMIVSWLNKRK

Nucleotide

• Length: 108 bp

>T103149 NZ_CP028734:229985-230092 [Escherichia coli]
ATGACGCTCGCAGAGTTGGGCATGGCCTTCTGGCATGATTTAGCGGTTCCGGTCATTACTGGCATTCTTGCCAGTATGAT
CGTGAGCTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT103149 NZ_CP028734:c229928-229870 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A3K0NFU8

Antitoxin