Detailed information of TA system TA103043

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 1149697..1150034
• Replicon: chromosome
• Accession: NZ_CP028720
• Organism: Enterococcus faecalis strain CVM N48037F

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: C7I32_RS06010
• Protein ID: WP_016619108.1
• Coordinates: 1149891..1150034 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1149697..1149959 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7I32_RS06005	1145005..1149696	+	4692	WP_010830710.1	WxL domain-containing protein	-
-	1149697..1149959	+	263	NuclAT_10	-	Antitoxin
-	1149698..1149747	-	50	NuclAT_14	-	-
C7I32_RS06010	1149891..1150034	-	144	WP_016619108.1	putative holin-like toxin	Toxin
C7I32_RS06015	1150366..1151982	-	1617	WP_002372620.1	phosphatase PAP2/LCP family protein	-
C7I32_RS06030	1152444..1153739	+	1296	WP_033626639.1	AAA family ATPase	-
C7I32_RS06035	1153748..1154380	+	633	WP_002358972.1	RloB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5191.13 Da
• Isoelectric Point: 8.6626

>T103043 WP_016619108.1 NZ_CP028720:c1150034-1149891 [Enterococcus faecalis]
MNVSTKTYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Nucleotide

• Length: 144 bp

>T103043 NZ_CP028720:c1150034-1149891 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAACCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 263 bp

>AT103043 NZ_CP028720:1149697-1149959 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGTGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATAGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Structures

Antitoxin