Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2152666..2152864 Replicon chromosome
Accession NZ_CP028468
Organism Staphylococcus aureus strain IT1-S

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag C5Y45_RS11030 Protein ID WP_075583739.1
Coordinates 2152760..2152864 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2152666..2152704 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5Y45_RS11010 2148769..2149434 - 666 WP_001024097.1 SDR family oxidoreductase -
C5Y45_RS11015 2149586..2149906 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C5Y45_RS11020 2149908..2150888 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
C5Y45_RS11025 2151154..2152245 + 1092 WP_000495680.1 hypothetical protein -
- 2152666..2152704 + 39 - - Antitoxin
C5Y45_RS11030 2152760..2152864 - 105 WP_075583739.1 hypothetical protein Toxin
C5Y45_RS11035 2152962..2153123 - 162 Protein_2044 helix-turn-helix domain-containing protein -
C5Y45_RS11045 2153541..2153699 + 159 WP_024928151.1 hypothetical protein -
C5Y45_RS11055 2154358..2155215 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
C5Y45_RS11060 2155283..2156065 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T101237 WP_075583739.1 NZ_CP028468:c2152864-2152760 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

>T101237 NZ_CP028468:c2152864-2152760 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTAATCAAGGCCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT101237 NZ_CP028468:2152666-2152704 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References