Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2214232..2214747 Replicon chromosome
Accession NZ_CP028426
Organism Gulosibacter molinativorax strain ON4

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag GMOLON4_RS10205 Protein ID WP_026936386.1
Coordinates 2214232..2214486 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GMOLON4_RS10210 Protein ID WP_026936385.1
Coordinates 2214487..2214747 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GMOLON4_RS10175 (GMOLON4_2063) 2209480..2210079 - 600 WP_026936390.1 acyltransferase -
GMOLON4_RS10180 (GMOLON4_2064) 2210484..2211167 + 684 WP_051266485.1 hypothetical protein -
GMOLON4_RS10185 (GMOLON4_2065) 2211186..2211722 + 537 WP_051266483.1 signal peptidase I -
GMOLON4_RS10190 (GMOLON4_2066) 2211706..2212434 + 729 WP_146137461.1 hypothetical protein -
GMOLON4_RS10195 (GMOLON4_2067) 2212431..2212619 + 189 WP_026936388.1 hypothetical protein -
GMOLON4_RS10200 (GMOLON4_2068) 2212620..2214206 + 1587 WP_026936387.1 choice-of-anchor G family protein -
GMOLON4_RS10205 (GMOLON4_2069) 2214232..2214486 - 255 WP_026936386.1 Txe/YoeB family addiction module toxin Toxin
GMOLON4_RS10210 (GMOLON4_2070) 2214487..2214747 - 261 WP_026936385.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GMOLON4_RS10215 (GMOLON4_2071) 2214889..2215428 - 540 WP_026936384.1 DUF3180 domain-containing protein -
GMOLON4_RS10220 (GMOLON4_2072) 2215425..2216546 - 1122 WP_084147390.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
GMOLON4_RS10225 (GMOLON4_2073) 2216776..2217648 - 873 WP_084147397.1 dihydropteroate synthase -
GMOLON4_RS10230 (GMOLON4_2074) 2217777..2218553 - 777 WP_051266481.1 GTP cyclohydrolase I -
GMOLON4_RS10235 2218553..2218675 - 123 WP_265576747.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10104.55 Da        Isoelectric Point: 8.0395

>T101149 WP_026936386.1 NZ_CP028426:c2214486-2214232 [Gulosibacter molinativorax]
VRLVWDQSAWEDYKHWQTADRKILKRINTLIEACLREPFTGIGKPEQLKYGAQGSWSRRITDEHRLVYMVLDDDLVILQA
RYHY

Download         Length: 255 bp

>T101149 NZ_CP028426:c2214486-2214232 [Gulosibacter molinativorax]
GTGCGTCTGGTCTGGGATCAGTCGGCCTGGGAAGACTACAAGCACTGGCAGACGGCCGATCGGAAGATCCTAAAGCGAAT
CAATACGTTAATTGAGGCATGCCTTCGCGAGCCGTTCACCGGAATTGGTAAGCCTGAACAACTGAAATATGGGGCGCAGG
GGTCGTGGTCGCGACGTATCACCGACGAGCACCGGCTGGTCTACATGGTGCTGGATGACGACCTTGTGATTCTGCAGGCC
CGCTATCATTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9737.86 Da        Isoelectric Point: 4.6768

>AT101149 WP_026936385.1 NZ_CP028426:c2214747-2214487 [Gulosibacter molinativorax]
MSISASEARKTLFPLIERVNENHEAVEIVSRKGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYDRARAGKIEFHALD
DVDEES

Download         Length: 261 bp

>AT101149 NZ_CP028426:c2214747-2214487 [Gulosibacter molinativorax]
ATGTCCATCAGTGCAAGCGAAGCGCGAAAGACTCTGTTCCCGCTCATTGAGCGTGTGAATGAGAACCACGAGGCCGTGGA
GATCGTTTCCCGCAAAGGTAATGCCGTCCTCATGCCAGCTGACGAGTACGCGGCATGGCAGGAAACGGCGTATCTATTCC
GCTCGCCGGCGAACGCTCGCCGACTGCTCGATGCGTATGATCGCGCCCGTGCAGGGAAGATTGAATTTCATGCACTCGAC
GACGTTGATGAGGAATCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References