Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 3077309..3077969 Replicon chromosome
Accession NZ_CP028349
Organism Pantoea vagans strain PV989

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag C9381_RS14670 Protein ID WP_107319888.1
Coordinates 3077616..3077969 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag C9381_RS14665 Protein ID WP_013358385.1
Coordinates 3077309..3077611 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9381_RS14645 3073150..3074175 - 1026 WP_179291192.1 ABC transporter permease -
C9381_RS14650 3074199..3075683 - 1485 WP_033783481.1 sugar ABC transporter ATP-binding protein -
C9381_RS14655 3075716..3076639 - 924 WP_033783482.1 sugar ABC transporter substrate-binding protein -
C9381_RS14665 3077309..3077611 - 303 WP_013358385.1 XRE family transcriptional regulator Antitoxin
C9381_RS14670 3077616..3077969 - 354 WP_107319888.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C9381_RS14675 3078255..3079343 - 1089 WP_107320194.1 YncE family protein -
C9381_RS14680 3079768..3081930 + 2163 WP_107319889.1 ferric-rhodotorulic acid/ferric-coprogen receptor FhuE -
C9381_RS14685 3082009..3082410 - 402 WP_033783588.1 cell envelope integrity/translocation protein TolA -
C9381_RS14690 3082508..3082789 - 282 WP_033783589.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-106)

Antitoxin

Cro/C1-type helix-turn-helix domain

(33-79)


Sequences

Toxin        


Download         Length: 118 a.a.        Molecular weight: 13546.60 Da        Isoelectric Point: 10.1023

>T101020 WP_107319888.1 NZ_CP028349:c3077969-3077616 [Pantoea vagans]
VWMIKTTERFDGWFTLLNDSDRACVLAALLVLRKKGPGLSRPYADTMKGSAYSNMKELRIQSRGDPVRAFFAFDPNRTAI
LLCDGNKAGNEKRFYREMLPVADREFTHWLKSFNHKE

Download         Length: 354 bp

>T101020 NZ_CP028349:c3077969-3077616 [Pantoea vagans]
GTGTGGATGATTAAAACGACAGAGCGGTTTGATGGCTGGTTTACGTTGCTTAATGACAGCGATCGCGCCTGTGTGCTGGC
TGCATTACTGGTGTTGCGGAAAAAGGGGCCGGGATTAAGCCGACCCTATGCGGATACGATGAAAGGTTCCGCTTATAGCA
ACATGAAGGAGTTACGTATCCAGAGCCGCGGCGACCCAGTAAGGGCTTTCTTTGCTTTTGACCCGAACCGCACGGCAATT
TTGCTGTGTGACGGTAATAAGGCGGGCAATGAAAAGCGATTTTATCGGGAGATGCTTCCGGTTGCCGATCGGGAATTCAC
ACACTGGCTAAAAAGCTTTAACCATAAGGAGTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10895.70 Da        Isoelectric Point: 5.7134

>AT101020 WP_013358385.1 NZ_CP028349:c3077611-3077309 [Pantoea vagans]
MGRTLEQLIADEKPEVVADAQAMATEILLNIHLAELREKVQKTQVEMAQALGITQPTVAGMEKPGRDLKLSTLKRYVDAA
GGKLRLVVELPDGSHFGFVV

Download         Length: 303 bp

>AT101020 NZ_CP028349:c3077611-3077309 [Pantoea vagans]
ATGGGCAGAACGCTGGAACAGCTTATTGCGGATGAAAAACCGGAAGTCGTTGCCGACGCACAGGCTATGGCGACCGAAAT
CCTGCTCAACATTCACCTTGCCGAGCTGCGTGAGAAAGTGCAGAAAACGCAGGTGGAAATGGCGCAGGCGCTGGGCATCA
CACAGCCGACCGTGGCGGGTATGGAAAAGCCGGGGCGTGACCTGAAGCTTTCCACGCTCAAACGCTACGTCGATGCGGCG
GGGGGGAAACTGCGGCTGGTGGTGGAGCTGCCGGATGGTTCCCACTTCGGGTTCGTGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References