Detailed information of TA system TA100944

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 72757..72999
• Replicon: plasmid unnamed1
• Accession: NZ_CP028286
• Organism: Enterococcus faecalis strain FDAARGOS_324

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: CEQ02_RS16020
• Protein ID: WP_107164701.1
• Coordinates: 72889..72999 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	72757..72848 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEQ02_RS15995	67863..67946	+	84	WP_001814874.1	23S rRNA methyltransferase attenuation leader peptide	-
CEQ02_RS16000	68071..68808	+	738	WP_001038790.1	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	-
CEQ02_RS16010	69163..69717	+	555	WP_000576156.1	recombinase family protein	-
CEQ02_RS16015	69721..72639	+	2919	WP_001240982.1	Tn3 family transposase	-
-	72757..72848	+	92	NuclAT_0	-	Antitoxin
-	72757..72848	+	92	NuclAT_0	-	Antitoxin
-	72757..72848	+	92	NuclAT_0	-	Antitoxin
-	72757..72848	+	92	NuclAT_0	-	Antitoxin
CEQ02_RS16020	72889..72999	-	111	WP_107164701.1	type I toxin-antitoxin system Fst family toxin	Toxin
CEQ02_RS16030	73250..73600	-	351	WP_033785382.1	hypothetical protein	-
CEQ02_RS16035	73597..74925	-	1329	WP_021164484.1	Y-family DNA polymerase	-
CEQ02_RS16040	75352..75654	-	303	WP_033785383.1	hypothetical protein	-
CEQ02_RS16045	75666..75875	-	210	WP_002382045.1	hypothetical protein	-
CEQ02_RS16050	75936..76160	-	225	WP_010708492.1	hypothetical protein	-
CEQ02_RS16055	76154..76441	-	288	WP_010708491.1	hypothetical protein	-
CEQ02_RS16060	76458..77078	-	621	WP_021732893.1	recombinase family protein	-
CEQ02_RS16065	77178..77981	-	804	WP_002367820.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	erm(B)	cylA / cylA / cylA / cylB / cylB / cylM / cylM / cylM / cylM / cylS / cylL / asa1 / cylI / cylA / cylB / cylM / cylS / cylL / cylR1 / cylR2	1..103690	103690

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4090.89 Da
• Isoelectric Point: 4.1672

>T100944 WP_107164701.1 NZ_CP028286:c72999-72889 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 111 bp

>T100944 NZ_CP028286:c72999-72889 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin

Nucleotide

• Length: 92 bp

>AT100944 NZ_CP028286:72757-72848 [Enterococcus faecalis]
TAAAAATATGTTATACTATAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin