Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 144119..144455 Replicon chromosome
Accession NZ_CP028285
Organism Enterococcus faecalis strain FDAARGOS_324

Toxin (Protein)


Gene name txpA Uniprot ID E2Z0W4
Locus tag CEQ02_RS01435 Protein ID WP_002381035.1
Coordinates 144312..144455 (-) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 144119..144168 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ02_RS01430 141121..144117 + 2997 WP_002385134.1 WxL domain-containing protein -
- 144119..144168 - 50 - - Antitoxin
CEQ02_RS01435 144312..144455 - 144 WP_002381035.1 putative holin-like toxin Toxin
CEQ02_RS01440 144785..146401 - 1617 WP_107164636.1 phosphatase PAP2/LCP family protein -
CEQ02_RS01450 147089..147727 + 639 WP_002378863.1 lytic polysaccharide monooxygenase -
CEQ02_RS01455 147991..148983 - 993 WP_002385136.1 biotin--[acetyl-CoA-carboxylase] ligase -
CEQ02_RS01460 149122..149337 + 216 WP_002354768.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5202.20 Da        Isoelectric Point: 10.0041

>T100937 WP_002381035.1 NZ_CP028285:c144455-144312 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

>T100937 NZ_CP028285:c144455-144312 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 50 bp

>AT100937 NZ_CP028285:c144168-144119 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6BWH2

Antitoxin

Download structure file

References