Detailed information of TA system TA100901

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 1445244..1445461
• Replicon: chromosome
• Accession: NZ_CP028213
• Organism: Bacillus subtilis strain SRCM102749

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: A0A6H0WKE8
• Locus tag: C7M27_RS07605
• Protein ID: WP_032721653.1
• Coordinates: 1445244..1445420 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	1445361..1445461 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7M27_RS07585	1440518..1442392	-	1875	Protein_1483	hypothetical protein	-
C7M27_RS07590	1442432..1442626	-	195	WP_072692657.1	hypothetical protein	-
C7M27_RS07595	1443578..1443904	+	327	WP_128740476.1	helix-turn-helix domain-containing protein	-
C7M27_RS07600	1444099..1444710	+	612	WP_128740475.1	hypothetical protein	-
-	1445203..1445303	-	101	NuclAT_0	-	-
-	1445203..1445303	-	101	NuclAT_0	-	-
-	1445203..1445303	-	101	NuclAT_0	-	-
-	1445203..1445303	-	101	NuclAT_0	-	-
C7M27_RS07605	1445244..1445420	+	177	WP_032721653.1	hypothetical protein	Toxin
-	1445361..1445461	-	101	-	-	Antitoxin
C7M27_RS07610	1445439..1445690	+	252	WP_080010576.1	hypothetical protein	-
C7M27_RS07615	1445735..1445923	+	189	WP_003230987.1	hypothetical protein	-
C7M27_RS07620	1446005..1447222	+	1218	WP_128740474.1	hypothetical protein	-
C7M27_RS07625	1447564..1447767	+	204	WP_128740473.1	hypothetical protein	-
C7M27_RS07630	1447831..1448034	+	204	WP_124048602.1	hypothetical protein	-
C7M27_RS07635	1448190..1448411	+	222	WP_128740472.1	hypothetical protein	-
C7M27_RS07640	1448436..1448747	+	312	WP_128740471.1	hypothetical protein	-
C7M27_RS07645	1448783..1448977	+	195	WP_128740470.1	hypothetical protein	-
C7M27_RS07650	1448977..1449213	+	237	WP_128740469.1	hypothetical protein	-
C7M27_RS07655	1449228..1449491	+	264	WP_128740468.1	hypothetical protein	-
C7M27_RS07660	1449478..1449699	+	222	WP_128740467.1	hypothetical protein	-
C7M27_RS07665	1449728..1449934	+	207	WP_128740466.1	hypothetical protein	-
C7M27_RS21850	1449969..1450127	+	159	WP_164914267.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1378847..1514792	135945

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6850.39 Da
• Isoelectric Point: 12.8833

>T100901 WP_032721653.1 NZ_CP028213:1445244-1445420 [Bacillus subtilis]
VLEKVGIVVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T100901 NZ_CP028213:1445244-1445420 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCAGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT100901 NZ_CP028213:c1445461-1445361 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCTGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Toxin

• AlphaFold DB: A0A6H0WKE8

Antitoxin