Detailed information of TA system TA100892

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 697872..698118
• Replicon: chromosome
• Accession: NZ_CP028212
• Organism: Bacillus subtilis strain SRCM102748

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: C7M26_RS22005
• Protein ID: WP_109789044.1
• Coordinates: 698026..698118 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	697872..698045 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7M26_RS04275	693786..694343	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
C7M26_RS04280	694445..696247	+	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
C7M26_RS04285	696257..696715	+	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
C7M26_RS04290	696915..697757	+	843	WP_003231327.1	hypothetical protein	-
-	697872..698045	+	174	-	-	Antitoxin
C7M26_RS22005	698026..698118	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
C7M26_RS04300	698407..698739	+	333	WP_026009814.1	hypothetical protein	-
C7M26_RS04305	698972..702577	+	3606	WP_032721999.1	membrane protein	-
C7M26_RS04310	702624..702959	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	688455..712121	23666

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T100892 WP_109789044.1 NZ_CP028212:c698118-698026 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T100892 NZ_CP028212:c698118-698026 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Nucleotide

• Length: 174 bp

>AT100892 NZ_CP028212:697872-698045 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin