Detailed information of TA system TA100886

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 542191..542408
• Replicon: chromosome
• Accession: NZ_CP028212
• Organism: Bacillus subtilis strain SRCM102748

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: C7M26_RS03190
• Protein ID: WP_017696861.1
• Coordinates: 542191..542367 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	542308..542408 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7M26_RS03175	537887..538165	-	279	WP_004399274.1	HU-related DNA-binding protein HupN	-
C7M26_RS03180	538409..540928	-	2520	WP_019712270.1	hypothetical protein	-
C7M26_RS03185	540968..541162	-	195	WP_003230986.1	hypothetical protein	-
-	542150..542250	-	101	NuclAT_1	-	-
-	542150..542250	-	101	NuclAT_1	-	-
-	542150..542250	-	101	NuclAT_1	-	-
-	542150..542250	-	101	NuclAT_1	-	-
C7M26_RS03190	542191..542367	+	177	WP_017696861.1	hypothetical protein	Toxin
-	542308..542408	-	101	-	-	Antitoxin
C7M26_RS03195	542386..542637	+	252	WP_080010576.1	hypothetical protein	-
C7M26_RS03200	542682..542870	+	189	WP_003230987.1	hypothetical protein	-
C7M26_RS03205	542986..543831	+	846	WP_160214969.1	GIY-YIG nuclease family protein	-
C7M26_RS03210	543850..545067	+	1218	WP_061891096.1	hypothetical protein	-
C7M26_RS03215	545386..545892	+	507	WP_061891097.1	hypothetical protein	-
C7M26_RS03220	546037..546489	+	453	WP_061891098.1	hypothetical protein	-
C7M26_RS03225	546486..546707	+	222	WP_061891099.1	hypothetical protein	-
C7M26_RS03230	546745..546999	+	255	WP_019712272.1	hypothetical protein	-
C7M26_RS03235	547047..547322	+	276	WP_019712273.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	486635..616393	129758

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6878.45 Da
• Isoelectric Point: 12.8833

>T100886 WP_017696861.1 NZ_CP028212:542191-542367 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T100886 NZ_CP028212:542191-542367 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGATAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT100886 NZ_CP028212:c542408-542308 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin