Detailed information of TA system TA100874

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-as-bsrH/-
• Location: 94512..94829
• Replicon: chromosome
• Accession: NZ_CP028212
• Organism: Bacillus subtilis strain SRCM102748

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: P54373
• Locus tag: C7M26_RS00620
• Protein ID: WP_004398662.1
• Coordinates: 94650..94829 (-)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	as-bsrH
Locus tag	-
Coordinates	94512..94726 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C7M26_RS00575	89881..90192	+	312	WP_003229923.1	YqbF domain-containing protein	-
C7M26_RS00580	90196..90591	+	396	WP_004398566.1	DUF3199 family protein	-
C7M26_RS00585	90588..90950	+	363	WP_003229925.1	YqbH/XkdH family protein	-
C7M26_RS00590	90947..91450	+	504	WP_003246050.1	HK97 gp10 family phage protein	-
C7M26_RS00595	91463..91900	+	438	WP_003229927.1	hypothetical protein	-
C7M26_RS00600	91897..92088	+	192	WP_010886574.1	hypothetical protein	-
C7M26_RS00605	92089..93489	+	1401	WP_003229929.1	phage tail sheath family protein	-
C7M26_RS00610	93492..93935	+	444	WP_003229930.1	phage tail tube protein	-
C7M26_RS00615	94189..94278	-	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
-	94512..94726	+	215	NuclAT_0	-	Antitoxin
-	94512..94726	+	215	NuclAT_0	-	Antitoxin
-	94512..94726	+	215	NuclAT_0	-	Antitoxin
-	94512..94726	+	215	NuclAT_0	-	Antitoxin
C7M26_RS00620	94650..94829	-	180	WP_004398662.1	type I toxin-antitoxin system toxin TxpA	Toxin
C7M26_RS00625	94975..95424	+	450	WP_032722171.1	phage portal protein	-
C7M26_RS00630	95466..95603	+	138	WP_021480099.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	73834..135497	61663

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T100874 WP_004398662.1 NZ_CP028212:c94829-94650 [Bacillus subtilis]
MSTYESLMVMIGFANLIGGIMTWVISLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T100874 NZ_CP028212:c94829-94650 [Bacillus subtilis]
ATGTCGACCTATGAATCTCTAATGGTCATGATCGGCTTTGCCAATTTAATAGGCGGGATTATGACATGGGTAATATCTCT
TTTAACATTATTATTCATGCTTAGAAAAAAAGACACTCATCCTATTTACATTACTGTAAAGGAAAAGTGTCTACACGAGG
ACCCTCCTATTAAAGGGTAG

Antitoxin

Nucleotide

• Length: 215 bp

>AT100874 NZ_CP028212:94512-94726 [Bacillus subtilis]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACTTGTTAATGTGTGTTACTTTCATG
AGAAATGCTAAAATATAAAAGCCAGAGTGTGGCAGCACTCTAGCTTTTAAAAAAGAAACTACCCTTTAATAGGAGGGTCC
TCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Toxin

• AlphaFold DB: A0A164X333

Antitoxin