Detailed information of TA system TA100810

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2788072..2788252
• Replicon: chromosome
• Accession: NZ_CP028190
• Organism: Staphylococcus aureus strain CFSAN018749

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: C9J86_RS14140
• Protein ID: WP_001801861.1
• Coordinates: 2788072..2788167 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2788195..2788252 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
C9J86_RS14105	2783216..2783842	+	627	WP_000669038.1	hypothetical protein	-
C9J86_RS14110	2783883..2784227	+	345	WP_000627550.1	DUF3969 family protein	-
C9J86_RS14115	2784325..2784897	+	573	WP_000414222.1	hypothetical protein	-
C9J86_RS14120	2785046..2786413	-	1368	WP_001093574.1	FRG domain-containing protein	-
C9J86_RS14125	2786413..2786982	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
C9J86_RS14130	2787175..2787621	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
C9J86_RS14140	2788072..2788167	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2788195..2788252	-	58	-	-	Antitoxin
C9J86_RS14145	2788290..2788391	+	102	WP_001791232.1	hypothetical protein	-
C9J86_RS14150	2788566..2788913	-	348	Protein_2669	DUF1433 domain-containing protein	-
C9J86_RS14160	2790672..2791115	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
C9J86_RS14165	2791115..2791557	-	443	Protein_2672	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T100810 WP_001801861.1 NZ_CP028190:2788072-2788167 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T100810 NZ_CP028190:2788072-2788167 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT100810 NZ_CP028190:c2788252-2788195 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin