Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 537566..537750 Replicon chromosome
Accession NZ_CP028190
Organism Staphylococcus aureus strain CFSAN018749

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag C9J86_RS03035 Protein ID WP_000482647.1
Coordinates 537643..537750 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 537566..537626 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J86_RS03010 533076..533243 - 168 Protein_563 hypothetical protein -
C9J86_RS03020 533474..535207 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
C9J86_RS03025 535232..536995 - 1764 WP_053865749.1 ABC transporter ATP-binding protein/permease -
- 537566..537626 + 61 - - Antitoxin
C9J86_RS03035 537643..537750 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
C9J86_RS03040 537884..538270 - 387 WP_000779351.1 flippase GtxA -
C9J86_RS03045 538538..539680 + 1143 WP_001176855.1 glycerate kinase -
C9J86_RS03050 539740..540399 + 660 WP_000831298.1 membrane protein -
C9J86_RS03055 540581..541792 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
C9J86_RS03060 541915..542388 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T100802 WP_000482647.1 NZ_CP028190:c537750-537643 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T100802 NZ_CP028190:c537750-537643 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT100802 NZ_CP028190:537566-537626 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References