Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 250726..251004 Replicon chromosome
Accession NZ_CP028190
Organism Staphylococcus aureus strain CFSAN018749

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag C9J86_RS01470 Protein ID WP_073392962.1
Coordinates 250900..251004 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 250726..250904 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J86_RS01450 245882..246202 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C9J86_RS01455 246204..247184 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
C9J86_RS01460 247450..248541 + 1092 WP_053865863.1 hypothetical protein -
C9J86_RS01465 248829..250474 + 1646 Protein_275 IS1182 family transposase -
- 250726..250904 + 179 - - Antitoxin
C9J86_RS01470 250900..251004 - 105 WP_073392962.1 hypothetical protein Toxin
C9J86_RS01480 251684..251842 + 159 WP_001792784.1 hypothetical protein -
C9J86_RS01490 252501..253358 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
C9J86_RS01495 253426..254208 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T100798 WP_073392962.1 NZ_CP028190:c251004-250900 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T100798 NZ_CP028190:c251004-250900 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT100798 NZ_CP028190:250726-250904 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References