Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1411504..1411688 Replicon chromosome
Accession NZ_CP028189
Organism Staphylococcus aureus strain CFSAN018750

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag C9J90_RS07395 Protein ID WP_000482647.1
Coordinates 1411581..1411688 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1411504..1411564 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J90_RS07370 1407034..1407201 - 168 WP_001790576.1 hypothetical protein -
C9J90_RS07380 1407432..1409165 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
C9J90_RS07385 1409190..1410953 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
C9J90_RS07395 1411581..1411688 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
C9J90_RS07400 1411822..1412208 - 387 WP_000779360.1 flippase GtxA -
C9J90_RS07405 1412466..1413608 + 1143 WP_001176863.1 glycerate kinase -
C9J90_RS07410 1413668..1414327 + 660 WP_000831298.1 membrane protein -
C9J90_RS07415 1414509..1415720 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
C9J90_RS07420 1415843..1416316 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T100792 WP_000482647.1 NZ_CP028189:c1411688-1411581 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T100792 NZ_CP028189:c1411688-1411581 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT100792 NZ_CP028189:1411504-1411564 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References