Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1126778..1127040 Replicon chromosome
Accession NZ_CP028189
Organism Staphylococcus aureus strain CFSAN018750

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag C9J90_RS05845 Protein ID WP_001802298.1
Coordinates 1126936..1127040 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 1126778..1126941 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J90_RS05825 1123018..1123683 - 666 WP_001024095.1 SDR family oxidoreductase -
C9J90_RS05830 1123835..1124155 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
C9J90_RS05835 1124157..1125137 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
C9J90_RS05840 1125403..1126494 + 1092 WP_000495681.1 hypothetical protein -
- 1126778..1126941 + 164 - - Antitoxin
C9J90_RS05845 1126936..1127040 - 105 WP_001802298.1 hypothetical protein Toxin
C9J90_RS05855 1127720..1127878 + 159 WP_001792784.1 hypothetical protein -
C9J90_RS05865 1128536..1129393 - 858 WP_000370930.1 Cof-type HAD-IIB family hydrolase -
C9J90_RS05870 1129461..1130243 - 783 WP_000908180.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T100789 WP_001802298.1 NZ_CP028189:c1127040-1126936 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T100789 NZ_CP028189:c1127040-1126936 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 164 bp

>AT100789 NZ_CP028189:1126778-1126941 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References