Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 846449..846629 Replicon chromosome
Accession NZ_CP028189
Organism Staphylococcus aureus strain CFSAN018750

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag C9J90_RS04185 Protein ID WP_001801861.1
Coordinates 846449..846544 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 846572..846629 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J90_RS04155 842504..843130 + 627 WP_000669028.1 hypothetical protein -
C9J90_RS04160 843157..843900 + 744 WP_175393121.1 exotoxin -
C9J90_RS04165 843927..844679 + 753 WP_000764922.1 staphylococcal enterotoxin type 27 -
C9J90_RS04170 844811..845367 - 557 Protein_795 ImmA/IrrE family metallo-endopeptidase -
C9J90_RS04175 845551..845997 - 447 WP_000747805.1 DUF1433 domain-containing protein -
C9J90_RS04185 846449..846544 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
C9J90_RS04190 847195..848891 - 1697 Protein_798 hypothetical protein -
C9J90_RS04195 848869..849723 - 855 WP_001069960.1 DNA adenine methylase -
C9J90_RS04200 849762..851027 - 1266 WP_000072555.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - selk 840740..870580 29840


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T100784 WP_001801861.1 NZ_CP028189:846449-846544 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T100784 NZ_CP028189:846449-846544 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT100784 NZ_CP028189:c846629-846572 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References