Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 78399..79056 | Replicon | plasmid pGMI17-002_1 |
| Accession | NZ_CP028170 | ||
| Organism | Salmonella enterica strain CFSAN064034 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | U3PDC3 |
| Locus tag | C6648_RS25890 | Protein ID | WP_000270043.1 |
| Coordinates | 78706..79056 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | C6648_RS25885 | Protein ID | WP_000124640.1 |
| Coordinates | 78399..78701 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C6648_RS25835 | 74033..74461 | + | 429 | WP_000591076.1 | hypothetical protein | - |
| C6648_RS25840 | 74519..74878 | + | 360 | WP_000422769.1 | hypothetical protein | - |
| C6648_RS25845 | 74878..75324 | + | 447 | WP_000919343.1 | hypothetical protein | - |
| C6648_RS25850 | 75321..75839 | + | 519 | WP_000210757.1 | nitrite reductase | - |
| C6648_RS25855 | 75839..76069 | + | 231 | WP_000972665.1 | hypothetical protein | - |
| C6648_RS25860 | 76056..76913 | + | 858 | WP_001167036.1 | hypothetical protein | - |
| C6648_RS26715 | 76825..77130 | + | 306 | WP_171820680.1 | hypothetical protein | - |
| C6648_RS25870 | 77133..77660 | + | 528 | WP_001210659.1 | thermonuclease family protein | - |
| C6648_RS25875 | 77718..77990 | + | 273 | WP_001043046.1 | HU family DNA-binding protein | - |
| C6648_RS25880 | 78079..78372 | + | 294 | WP_001239998.1 | hypothetical protein | - |
| C6648_RS25885 | 78399..78701 | - | 303 | WP_000124640.1 | XRE family transcriptional regulator | Antitoxin |
| C6648_RS25890 | 78706..79056 | - | 351 | WP_000270043.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| C6648_RS25895 | 79219..79767 | + | 549 | WP_001061573.1 | hypothetical protein | - |
| C6648_RS25905 | 80108..80302 | + | 195 | WP_000343597.1 | hypothetical protein | - |
| C6648_RS25910 | 80313..80684 | + | 372 | WP_000516918.1 | hypothetical protein | - |
| C6648_RS25915 | 80677..81147 | + | 471 | WP_001281821.1 | hypothetical protein | - |
| C6648_RS25920 | 81162..81497 | - | 336 | WP_000683477.1 | hypothetical protein | - |
| C6648_RS25925 | 81594..82082 | + | 489 | WP_001273096.1 | DUF1643 domain-containing protein | - |
| C6648_RS25930 | 82085..82582 | + | 498 | WP_000062185.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..177712 | 177712 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 17237.68 Da Isoelectric Point: 5.5500
>T100760 WP_000270043.1 NZ_CP028170:c79056-78706 [Salmonella enterica]
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FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
Download Length: 351 bp
>T100760 NZ_CP028170:c79056-78706 [Salmonella enterica]
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Antitoxin
Download Length: 101 a.a. Molecular weight: 14882.85 Da Isoelectric Point: 5.5500
>AT100760 WP_000124640.1 NZ_CP028170:c78701-78399 [Salmonella enterica]
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Download Length: 303 bp
>AT100760 NZ_CP028170:c78701-78399 [Salmonella enterica]
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Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|