Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1218547..1218731 Replicon chromosome
Accession NZ_CP028165
Organism Staphylococcus aureus strain CFSAN064037

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag C9J78_RS06395 Protein ID WP_000482647.1
Coordinates 1218624..1218731 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1218547..1218607 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C9J78_RS06370 1214001..1214168 - 168 WP_031901225.1 hypothetical protein -
C9J78_RS06380 1214399..1216132 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
C9J78_RS06385 1216157..1217920 - 1764 WP_103145546.1 ABC transporter ATP-binding protein/permease -
- 1218547..1218607 + 61 - - Antitoxin
C9J78_RS06395 1218624..1218731 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
C9J78_RS06400 1218865..1219251 - 387 WP_000779350.1 flippase GtxA -
C9J78_RS06405 1219519..1220661 + 1143 WP_001176867.1 glycerate kinase -
C9J78_RS06410 1220721..1221380 + 660 WP_000831298.1 membrane protein -
C9J78_RS06415 1221563..1222774 + 1212 WP_001191927.1 multidrug effflux MFS transporter -
C9J78_RS06420 1222897..1223370 - 474 WP_000456488.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T100724 WP_000482647.1 NZ_CP028165:c1218731-1218624 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T100724 NZ_CP028165:c1218731-1218624 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT100724 NZ_CP028165:1218547-1218607 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References